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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1870887Generated: October 25, 2026

4-Bromo-3-methylaniline → 1-(4-Bromo-3-methylphenyl)-3,3-dimethylpyrrolidin-2-one

https://huagongshe.com/reaction/1870887

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-3-methylanilineHCID 23359—
Reactant2,2-Dimethyl-4-butyrolactoneHCID 94746—
Product1-(4-Bromo-3-methylphenyl)-3,3-dimethylpyrrolidin-2-oneHCID 18694237—

Reaction Steps

The title compound was prepared from 4-bromo-3-methylaniline and α,α-dimethyl-γ-butyrolactone following a similar procedure to Description 20, as a pink solid (53%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06100272
Source datasetuspto-grants-2000_08
ORD IDord-4f3c276187254393998827fcd11434ea
Source noteuspto-grants-2000_08