HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1H-Inden-4-ol, 2,3-dihydro-, 4-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-Hydroxyindan | HCID 74233 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1H-Inden-4-ol, 2,3-dihydro-, 4-acetate | HCID 57183190 | 115% |
Reaction Steps
A mixture of 2,3-dihydro-1H-inden-4-ol (0.37 mol) and acetic anhydride (0.37 mol) in sulfuric acid (300 mol) was stirred for 1 hour at room temperature. The reaction mixture was poured out into a mixture of water and 1,1'-oxybisethane. The organic layer was separated, dried (MgSO4), filtered and the solvent was evaporated, yielding 75 g (>100% crude residue) of 2,3-dihydro-1H-inden-4-ol acetate (ester) (interm. 1-a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06100268 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-fefbaee0ddd446899d82e3d3b66c451b |
| Source note | uspto-grants-2000_08 |