Diethyl Ether → HCID 18694782, compound

Participants

Reaction Steps

Using the procedure of Stage B of Example 1, 5.65 g of the product of Stage B and 1.45 ml of hydrazine hydrate in 75 ml of ethanol were reacted to obtain 3.8 g of crude product which was dissolved in 4 ml of tetrahydrofuran. Then, 1.87 g of fumaric acid in solution in 20 ml of methanol were added and 10 ml of ether were added. The crystals formed were separated and dried at 80° C. under reduced pressure to obtain 3.77 g of the fumarate of the expected product melting at 160-162° C.

Provenance & Evidence