HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → HCID 70228365, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | Benzoic Acid | HCID 243 | — |
| Reactant | 2-Methyl-3-butyn-2-ol | HCID 8258 | — |
| Reactant | N-Benzylidene-3-bromoaniline | HCID 525548 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Product | HCID 70228365 | HCID 70228365 | — |
Reaction Steps
The procedure was the same as in Example 2 using benzaldehyde free of benzoic acid, through the steps intended for the ex situ formation of the N-benzylidene 3-aminophenylbromide and the catalyzed reaction with 2-methyl-3-butyn-2-ol, with the exception that no benzoic acid was added. Upon the addition of the CuI, an apparent precipitation of Pd was observed (not seen in the procedure of Example 2). After several hours of reflux no reaction to form an aminophenylacetylene dimethylcarbinol, with or without the N-benzylidene moiety, could be observed by thin-layer chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06100429 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-23b7807da13d4987b2a5b20cc96feb11 |
| Source note | uspto-grants-2000_08 |