4-(Chlorosulfonyl)-2-hydroxybenzoic acid → HCID 10122282, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure in Example 1, step 2, using (2-n-butyl-benzofuran-3-yl)-(2'-hydroxy-[1,1';3',1"]terphenyl-5'-yl)-methanone (0.136 g, 0.305 mmol) and 4-chlorosulphonyl-2-hydroxybenzoic acid (0.144 g, 6.09 mmol) to give 0.080 g (38%) of the title compound as a white solid, mp 190-197° C.; 1H NMR (DMSO-d6) δ 0.77 (t, 3 H), 1.22 (sextet, 2 H), 1.63 (quintet, 2 H), 2.83 (t, 2 H), 6.55 (d, 1 H), 6.66 (dd, 1 H), 7.28-7.38 (m, 8 H), 7.41-7.43 (m, 4 H), 7.51 (dd, 1 H), 7.57 (d, 1 H), 7.64 (d, 1 H), 7.74 (s, 2 H). IR (KBr) 2900, 1675, 1390 and 1190 cm-1. mass spectrum (-ESI), m/z 645 (M-H). Anal. Calcd. for C38H30O8S.2H2O: C, 66.85; H, 5.02; N, 0.00. Found: C, 66.80; H, 4.88; N, 0.07.

Provenance & Evidence