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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871369Generated: November 1, 2026

1-Bromohexane → (cis)-4-(3,4-Dimethoxyphenyl)-2-(n-hexyl)-4a,5,8,8a-tetrahydro-2-H-phthalazin-1-one

https://huagongshe.com/reaction/1871369

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-BromohexaneHCID 8101—
Reactantcis-4-(3,4-Dimethoxyphenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-oneHCID 10935039—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-2-methyl-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 70003942—
Product(cis)-4-(3,4-Dimethoxyphenyl)-2-(n-hexyl)-4a,5,8,8a-tetrahydro-2-H-phthalazin-1-oneHCID 70001935—

Reaction Steps

Prepared from compound 3 and 1-bromohexane as described for compound 8. Purified by chromatography; crystallized from petroleum ether (60-80° C.) at -20° C. M.p. 74-75° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103718
Source datasetuspto-grants-2000_08
ORD IDord-b56d806130eb43f590d3ff44bdec9158
Source noteuspto-grants-2000_08