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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871374Generated: November 2, 2026

Bromocyclopentane → (cis)-4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-cyclopentyl-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one

https://huagongshe.com/reaction/1871374

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromocyclopentaneHCID 8728—
Reactantcis-4-(3-Cyclopentyloxy-4-methoxyphenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-oneHCID 11056941—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-2-methyl-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 70003942—
Product(cis)-4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-cyclopentyl-4a,5,8,8a-tetrahydro-2H-phthalazin-1-oneHCID 70002575—

Reaction Steps

Prepared from compound 5 and cyclopentylbromide as described for compound 8. Crystallized from diethyl ether. M.p. 144-145° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103718
Source datasetuspto-grants-2000_08
ORD IDord-f3fefad620204b2d886641745b03633c
Source noteuspto-grants-2000_08