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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871379Generated: November 2, 2026

Propargyl bromide → HCID 86755600, compound

https://huagongshe.com/reaction/1871379

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropargyl bromideHCID 7842—
ReactantSodium ethoxideHCID 2723922—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 10913208—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-2-methyl-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 70003942—
ProductHCID 86755600HCID 86755600—

Reaction Steps

Prepared from compound 1 and propargylbromide as described for compound 8, using sodium ethanolate instead of sodium hydride. Purified by chromatography (dichloromethane). Crystallized from methanol. M.p. 118-121° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103718
Source datasetuspto-grants-2000_08
ORD IDord-1bba022b75974a49b37ce7185d6a0eb4
Source noteuspto-grants-2000_08