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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871396Generated: November 2, 2026

4-Hydrazinobenzoic acid → (cis)-4-(4-(3,4-Dimethoxyphenyl)-1-oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl)benzoic acid

https://huagongshe.com/reaction/1871396

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydrazinobenzoic acidHCID 12089—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-2-(2-hydroxy-1-ethyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 86755609—
Product(cis)-4-(4-(3,4-Dimethoxyphenyl)-1-oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl)benzoic acidHCID 86755612—

Reaction Steps

Prepared from compound C and 4-hydrazinobenzoic acid as described for compound 35. Purified by chromatography and crystallized from ethyl acetate. M.p. 198°-199° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103718
Source datasetuspto-grants-2000_08
ORD IDord-ef8a6174092248aa88d4b75a4077082f
Source noteuspto-grants-2000_08