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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871413Generated: October 30, 2026

3-Methoxybenzyl chloride → (cis)-4-(3,4-Dimethoxyphenyl)-2-(3-methoxybenzyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one

https://huagongshe.com/reaction/1871413

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methoxybenzyl chlorideHCID 69994—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 10913208—
Reactant(cis)-2-Benzyl-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 70001660—
Product(cis)-4-(3,4-Dimethoxyphenyl)-2-(3-methoxybenzyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 70003164—

Reaction Steps

Prepared from compound 1 and 3-methoxybenzylchloride as described for compound 78. Crystallized from methanol. M.p. 115° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103718
Source datasetuspto-grants-2000_08
ORD IDord-c3b3f95bcc0b4b4f9f42972bccb4116a
Source noteuspto-grants-2000_08