2-Hydrazinopyridine → HCID 70001955, compound

HRID 1871419Notes

Reaction equation

HRID 1871419 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][NH2:8].[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:19]2[C@H:28]3[C@H:23]([CH2:24][CH2:25][CH2:26][CH2:27]3)[C:22](=[O:29])N(CCO)N=2)[CH:14]=[CH:15][C:16]=1[O:17][CH3:18]>>[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:19]2[C@H:28]3[C@H:23]([CH2:24][CH:25]=[CH:26][CH2:27]3)[C:22](=[O:29])[N:7]([C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=3)[N:8]=2)[CH:14]=[CH:15][C:16]=1[O:17][CH3:18]

Participants

3

Reactant 2

HCID 786452-HydrazinopyridineHCID 86755609(cis)-4-(3,4-Dimethoxyphenyl)-2-(2-hydroxy-1-ethyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one

Product 1

HCID 70001955HCID 70001955, compound

Procedure

Prepared from compound C and 2-pyridylhydrazine as described for compound 35. Purified by chromatography (ethyl acetate) and crystallized from ethyl acetate/diethyl ether. M.p. 147°-148° C.

Workup

  1. customPurified by chromatography (ethyl acetate)
  2. customcrystallized from ethyl acetate/diethyl ether

Sources & evidence

ORD record
ord-296ed9dd66474c7f8d9c70572ac63355
Source dataset
uspto-grants-2000_08
Patent number
US06103718

Reaction notes

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