Picolyl chloride hydrochloride → HCID 70002048, compound

HRID 1871420Notes

Reaction equation

HRID 1871420 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C@H:20]3[C@H:15]([CH2:16][CH2:17][CH2:18][CH2:19]3)[C:14](=[O:21])[NH:13][N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].Cl.[N:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH2:29]Cl>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C@H:20]3[C@H:15]([CH2:16][CH2:17][CH2:18][CH2:19]3)[C:14](=[O:21])[N:13]([CH2:29][C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][N:23]=3)[N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

3

Reactant 2

HCID 23392Picolyl chloride hydrochlorideHCID 10913208(cis)-4-(3,4-Dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one

Product 1

HCID 70002048HCID 70002048, compound

Procedure

Prepared from compound 1 and 2-picolylchloride hydrochloride as described for compound 105. Crystallized from diethyl ether. M.p. 181°-182° C.

Workup

  1. customCrystallized from diethyl ether

Sources & evidence

ORD record
ord-f44c72d451b44a6693d46b3bc6cd4e76
Source dataset
uspto-grants-2000_08
Patent number
US06103718

Reaction notes

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