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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871421Generated: October 31, 2026

Picolyl chloride hydrochloride → (cis)-4-(3,4-Dimethoxyphenyl)-2-(2-pyridylmethyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one

https://huagongshe.com/reaction/1871421

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPicolyl chloride hydrochlorideHCID 23392—
Reactantcis-4-(3,4-Dimethoxyphenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-oneHCID 10935039—
Product(cis)-4-(3,4-Dimethoxyphenyl)-2-(2-pyridylmethyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-oneHCID 70003838—

Reaction Steps

Prepared from compound 3 and 2-picolylchloride hydrochloride as described for compound 105. Crystallized from diethyl ether. M.p. 146°-147° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103718
Source datasetuspto-grants-2000_08
ORD IDord-d111eb7d4464495eaa0b24243f430255
Source noteuspto-grants-2000_08