2-Hydrazinoquinoxaline → HCID 70003437, compound

HRID 1871427Notes

Reaction equation

HRID 1871427 reaction equation
[NH:1]([C:3]1[CH:4]=[N:5][C:6]2[CH:12]=[CH:11][CH:10]=[CH:9][C:7]=2[N:8]=1)[NH2:2].[CH3:13][O:14][C:15]1[CH:16]=[C:17]([C:23]2[C@H:32]3[C@H:27]([CH2:28][CH2:29][CH2:30][CH2:31]3)[C:26](=[O:33])N(CCO)N=2)[CH:18]=[CH:19][C:20]=1[O:21][CH3:22]>>[CH3:13][O:14][C:15]1[CH:16]=[C:17]([C:23]2[C@H:32]3[C@H:27]([CH2:28][CH:29]=[CH:30][CH2:31]3)[C:26](=[O:33])[N:1]([C:3]3[CH:4]=[N:5][C:6]4[CH:12]=[CH:11][CH:10]=[CH:9][C:7]=4[N:8]=3)[N:2]=2)[CH:18]=[CH:19][C:20]=1[O:21][CH3:22]

Participants

3

Reactant 2

HCID 2898472-HydrazinoquinoxalineHCID 86755609(cis)-4-(3,4-Dimethoxyphenyl)-2-(2-hydroxy-1-ethyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one

Product 1

HCID 70003437HCID 70003437, compound

Procedure

Prepared from compound C and 2-hydrazino-1,4-benzodiazine as described for compound 35. Purified by chromatography and crystallized from diethyl ether. M.p. 154°-156° C.

Workup

  1. customPurified by chromatography
  2. customcrystallized from diethyl ether

Sources & evidence

ORD record
ord-3aef4379696b42aca8eb16d013cb74c6
Source dataset
uspto-grants-2000_08
Patent number
US06103718

Reaction notes

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