4-Benzyloxybenzyl chloride → HCID 70003379, compound

HRID 1871441Notes

Reaction equation

HRID 1871441 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C@H:20]3[C@H:15]([CH2:16][CH2:17][CH2:18][CH2:19]3)[C:14](=[O:21])[NH:13][N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[CH2:22]([O:29][C:30]1[CH:37]=[CH:36][C:33]([CH2:34]Cl)=[CH:32][CH:31]=1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.C(N1N=C(C2C=CC(OC)=C(OC)C=2)[C@H]2[C@H](CCCC2)C1=O)C1C=CC=CC=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C@H:20]3[C@H:15]([CH2:16][CH2:17][CH2:18][CH2:19]3)[C:14](=[O:21])[N:13]([CH2:34][C:33]3[CH:36]=[CH:37][C:30]([O:29][CH2:22][C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=4)=[CH:31][CH:32]=3)[N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

4

Reactant 3

HCID 700424-Benzyloxybenzyl chlorideHCID 10913208(cis)-4-(3,4-Dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 70001660(cis)-2-Benzyl-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one

Product 1

HCID 70003379HCID 70003379, compound

Procedure

Prepared from compound 1 and 4-benzyloxybenzylchloride as described from compound 78. Purified by chromatography (dichloromethane) and isolated as a colourless oil.

Workup

  1. customPurified by chromatography (dichloromethane)
  2. customisolated as a colourless oil

Sources & evidence

ORD record
ord-55cc57fad4e947acbdf8d9c4cae40808
Source dataset
uspto-grants-2000_08
Patent number
US06103718

Reaction notes

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