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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871443Generated: November 4, 2026

(Thian-4-yl)hydrazine → (cis)-4-(3,4-Dimethoxyphenyl)-2-(tetrahydrothiopyran-4-yl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one

https://huagongshe.com/reaction/1871443

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Thian-4-yl)hydrazineHCID 22593899—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-2-(2-hydroxy-1-ethyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 86755609—
Product(cis)-4-(3,4-Dimethoxyphenyl)-2-(tetrahydrothiopyran-4-yl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-oneHCID 86755632—

Reaction Steps

Prepared from compound C and 4-hydrazinotetrahydrothiopyran as described for compound 35. Crystallized from methanol. M.p. 140°-141° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103718
Source datasetuspto-grants-2000_08
ORD IDord-8ecf23dab85c4cfbac4a16871bb8bc5f
Source noteuspto-grants-2000_08