HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 5-(3-nitrophenyl)tetrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-Nitrobenzonitrile | HCID 12090 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Product | 5-(3-nitrophenyl)tetrazole | HCID 285129 | — |
Reaction Conditions
| Temperature | 120 °C |
|---|
Reaction Steps
A mixture of 14.8 g of 4-nitrobenzonitril, 32 g of ammoniumchloride and 39 g of sodium azide in 150 ml of DMF was heated for 2 h at 120° C. After evaporating the solvent, the residue was partitioned between 2N hydrochloric acid and ethyl acetate. The organic layer was dried and evaporated. The residue was washed with ether and dried. M.p. 101-102° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06103718 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-73ac118cbba84f05af0cdabac430908d |
| Source note | uspto-grants-2000_08 |