2-Fluorobenzenesulphonyl chloride → HCID 18691622, compound

HRID 1871523Notes

Reaction equation

HRID 1871523 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8](Cl)(=[O:10])=[O:9].[NH2:12][C:13]1[CH:14]=[C:15]([CH2:19][CH2:20][NH:21][CH:22](C(OC(C)(C)C)=O)[CH2:23][CH3:24])[CH:16]=[CH:17][CH:18]=1>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH:12][C:13]1[CH:14]=[C:15]([CH2:19][CH2:20][NH:21][CH2:22][CH2:23][CH3:24])[CH:16]=[CH:17][CH:18]=1)(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 1377612-Fluorobenzenesulphonyl chlorideHCID 18691620HCID 18691620, compound

Product 1

HCID 18691622HCID 18691622, compound

Procedure

Using procedure 4, 2-fluorobenzenesulfonyl chloride was added to 2-(3-aminophenyl)ethyl-1-(tert-butoxycarbonyl)propylamine (13) to give the title compound as a solid, m.p. 165-169° C.

Sources & evidence

ORD record
ord-32c925f986d84ef598b35f8c7dd1334c
Source dataset
uspto-grants-2000_08
Patent number
US06103766

Reaction notes

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