Potassium Hydroxide → HCID 54393095, compound

HRID 1871607Notes

Reaction equation

HRID 1871607 reaction equation
[OH-].[K+].[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:5]=1[C:11]([OH:25])([CH2:19][N:20]1[CH:24]=[N:23][CH:22]=[N:21]1)[CH:12]([CH3:18])[CH2:13][S:14]C(=O)C>CO>[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:5]=1[C@@:11]([OH:25])([CH2:19][N:20]1[CH:24]=[N:23][CH:22]=[N:21]1)[C@@H:12]([CH3:18])[CH2:13][SH:14]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 86753721HCID 86753721, compound

Product 1

HCID 54393095HCID 54393095, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

Under nitrogen atmosphere at room temperature a solution of potassium hydroxide (0.266 g; 4,74 mmoles) in methanol (40 ml) was dropped into a solution of thioacetic acid S-[3-(2,4-dichlorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butyl] ester, prepared as described in Example 6 (1.72 g; 4.6 mmoles) in methanol (40 ml).

Workup

  1. customprepared

Sources & evidence

ORD record
ord-de921969ea2640f2b431300771c96a07
Source dataset
uspto-grants-2000_08
Patent number
US06103909

Reaction notes

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