HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871645Generated: November 1, 2026
Aniline → Ethyl 3-(4-benzyloxyphenyl)-2-(phenylamino)propionate
https://huagongshe.com/reaction/1871645
Participants
| Role | Name | HCID | Charge |
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| Reactant | Aniline | HCID 6115 | — |
| Reactant | Ethyl 3-(4-benzyloxyphenyl)-2-methanesulfonyloxypropionate | HCID 18625936 | — |
| Product | Ethyl 3-(4-benzyloxyphenyl)-2-(phenylamino)propionate | HCID 18625698 | — |
Reaction Steps
A mixture of 4.00 g of ethyl 3-(4-benzyloxyphenyl)-2-methanesulfonyloxypropionate and 5 ml of aniline was stirred at 110° C. for 24 hours. The reaction mixture was purified by silica gel column chromatography (ethyl acetate:hexane=1:4) to obtain 3.94 g of the desired compound as a syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06103907 |
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| Source dataset | uspto-grants-2000_08 |
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| ORD ID | ord-fb9a85e5c3224a739f9edcd7959c908c |
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| Source note | uspto-grants-2000_08 |
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