HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → Diethyl 2-(4-benzyloxybenzyl)-2-phenoxymalonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-Benzyloxybenzyl chloride | HCID 70042 | — |
| Reactant | 1,3-Diethyl 2-phenoxypropanedioate | HCID 2305167 | — |
| Product | Diethyl 2-(4-benzyloxybenzyl)-2-phenoxymalonate | HCID 18626030 | 62.1% |
Reaction Steps
Reaction and post-treatment were carried out according to Reference example 12(a) using 2.81 g of diethyl phenoxymalonate, 2.59 g of 4-benzyloxybenzyl chloride and 530 mg of sodium hydride (55% oil suspension) to obtain 3.10 g of the desired compound as a syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06103907 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-330a22de0731478cbcd8865d4a5ab13a |
| Source note | uspto-grants-2000_08 |