HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 53678340, compound → HCID 54041342, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 53678340 | HCID 53678340 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54041342 | HCID 54041342 | 46% |
Reaction Steps
440 mg (0.87 mmol) (R)-1-[5-[(R)-2-benzyloxycarbonyl-pyrrolidin-1-yl]-5-oxo-pentanoyl]-pyrrolidine-2-carboxylic acid benzyl ester in 100 ml ethanol were hydrogenated in the presence of 40 mg 5% Pd on carbon. Filtration and evaporation of the solvent yielded 130 mg (46%) (R)-1-[5-[(R)-2-carboxy-pyrrolidin-1-yl]-5-oxo-pentanoyl]-pyrrolidine-2-carboxylic acid as colorless oil. MS-ISP: 327 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06103910 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-b0b825248e19413b9c3591c7ea25cbb4 |
| Source note | uspto-grants-2000_08 |