HCID 54258738, compound → HCID 54185753, compound

Participants

Reaction Steps

A solution of 46 mg (0.084 mmol) (R)-1-[[3-[2-[(R)-2-tert -butoxycarbonyl-pyrrolidin-1-yl]-2-oxo-ethoxy]-5-hydroxy-phenoxy]-acetyl]-pyrrolidine-2-carboxylic acid tert-butyl ester in 1 ml trifluoroacetic acid was stirred for 4 h at room temperature. The solvent was removed in vacuo and the residue suspended in 5 ml ether. The resulting suspension was stirred overnight. Filtration and drying gave 35 mg (96%) of the title compound as a light brown powder. MS m/e (%): 435 (M-H-, 100).

Provenance & Evidence