Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871745Generated: November 2, 2026

m-Phenylenediacetic acid → HCID 54405893, compound

https://huagongshe.com/reaction/1871745

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Phenylenediacetic acidHCID 29788—
Reactantbenzyl (2R)-pyrrolidine-2-carboxylate hydrochlorideHCID 22827650—
SolventEthyl AcetateHCID 8857—
ProductHCID 54405893HCID 5440589384%

Reaction Steps

Using General Procedure A with 2.0 g (8.2 mmol) D-Proline benzyl ester hydrochloride and 800 mg (4.1 mmol) 1,3-phenylenediacetic acid afforded, after flash chromatography (EtOAc), 1.93 g (84%) of the title compound as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103910
Source datasetuspto-grants-2000_08
ORD IDord-a118c4b16b4c493ea2b265c4b0c045bb
Source noteuspto-grants-2000_08