Hexamethyldisilazane → Lithium Hexamethyldisilazide

Participants

Reaction Steps

Under a nitrogen atmosphere, 9.93 g (94.4 mmols) of bis(trimethylsilyl)amine dried and purged with nitrogen and 100 ml of hexane dried and purged with nitrogen were placed in a 300-ml Schlenk flask sufficiently purged with nitrogen, and the resultant solution was then cooled on a dry ice-ethanol bath. Next, 57.5 ml of a 1.64 mol/l n-butyllithium (94.4 mmols) solution in hexane was added dropwise to this solution, followed by stirring at room temperature for 12 hours. The solvent was distilled off under reduced pressure to obtain lithiumbis(trimethylsilyl)amide in the state of a white solid.

Provenance & Evidence