Iodoethane → HCID 12051933, compound

Participants

Reaction Steps

The title compound from Example 1 (0.30 g) was dissolved in dry DMF (10 mL) and added NaH (62 mg; 60% in oil) at room temperature under a nitrogen atmosphere. The reaction mixture was stirred for 5 mins., and then added EtI (0.2 mL) and continued for an additional 24 h. The reaction mixture was partitioned between ethyl acetate (25 mL) and water (25 mL), washed the organic layer with brine, dried, and stripped in vacuum to yield a pale yellow oil. The sample was purified by flash column chromatography (1:100 MeOH +CH2Cl2) to afford the title compound as a colorlesss oil (0.16 g). Elemental analysis for C19H25BrN6 : Theory C: 54.68, H: 6.05 Found: C: 54.66, H: 6.02.

Provenance & Evidence