5-(5h-Dibenzo[a,d]cyclohepten-5-yl)-2,4(1h,3h)-pyrimidinedione → HCID 86755651, compound

HRID 1871971Notes

Reaction equation

HRID 1871971 reaction equation
Cl[C:2]1[N:7]=[C:6]([S:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])[C:5]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][C:21]([O:23][CH3:24])=[O:22])=[CH:16][CH:15]=2)=[CH:4][N:3]=1.[CH:25]1[C:35]2[CH:34]=[CH:33][C:32]3[CH:36]=[CH:37][CH:38]=[CH:39][C:31]=3[CH:30]([C:40]3[C:41](=[O:47])[NH:42][C:43](=[O:46])[NH:44][CH:45]=3)[C:29]=2[CH:28]=[CH:27][CH:26]=1>>[CH:25]1[C:35]2[CH:34]=[CH:33][C:32]3[CH:36]=[CH:37][CH:38]=[CH:39][C:31]=3[CH:30]([C:40]3[C:41](=[O:47])[NH:42][C:43](=[O:46])[N:44]([C:2]4[N:7]=[C:6]([S:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])[C:5]([C:14]5[CH:19]=[CH:18][C:17]([CH2:20][C:21]([O:23][CH3:24])=[O:22])=[CH:16][CH:15]=5)=[CH:4][N:3]=4)[CH:45]=3)[C:29]=2[CH:28]=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 110986755-(5h-Dibenzo[a,d]cyclohepten-5-yl)-2,4(1h,3h)-pyrimidinedioneHCID 86755649HCID 86755649, compound

Product 1

HCID 86755651HCID 86755651, compound

Procedure

The subtitle compound was prepared from the product of step (iv) (0.58 g) and the product of example 1 step (iv) (0.48 g) by the method of example 2 step (i). Purification was by chromatography eluting with 2% methanol in chloroform. Yield 0.4 g.

Workup

  1. customPurification
  2. washeluting with 2% methanol in chloroform

Sources & evidence

ORD record
ord-d56c68c43b874b3390bba4170628580a
Source dataset
uspto-grants-2000_08
Patent number
US06107297

Reaction notes

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