HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzyl chloride → 4,5-Dihydro-2-[2-[2-[3-Methoxyphenyl]ethyl]-4-methylphenyl]-4,4-dimethyloxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzyl chloride | HCID 69994 | — |
| Reactant | 2-[2,4-Dimethylphenyl]-4,5-dihydro-4,4-dimethyloxazole | HCID 22117273 | — |
| Product | 4,5-Dihydro-2-[2-[2-[3-Methoxyphenyl]ethyl]-4-methylphenyl]-4,4-dimethyloxazole | HCID 18689703 | — |
Reaction Steps
The subtitle compound was prepared from the product of example 15 step (iii) (20 g) and 3-methoxybenzyl chloride (17.4 ml) by the method of example 15 step (iv). Purification was by chromatography eluting with 5-10% ethyl acetate in isohexane. Yield 20.53 g. MS: APCI(+ve): 324 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06107297 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-bc4350c96f7f451a94aa710a435535ca |
| Source note | uspto-grants-2000_08 |