HCID 18689744, compound → HCID 18689746, compound

HRID 1872012Notes

Reaction equation

HRID 1872012 reaction equation
[NH2:1][CH2:2][C:3]([NH:5][C:6]1[S:7][CH:8]=[C:9]([CH2:11][C:12]#[N:13])[N:10]=1)=[O:4].[CH2:14]([C:16]1[CH:59]=[CH:58][C:19]2[CH:20]([C:30]3[C:31](=[O:57])[NH:32][C:33](=[O:56])[N:34]([C:36]4[CH:41]=[CH:40][N:39]=[C:38](NCC(NC5SC=C(CC(O)=O)N=5)=O)[N:37]=4)[CH:35]=3)[C:21]3[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][C:22]=3[CH:23]=[CH:24][C:18]=2[CH:17]=1)[CH3:15]>>[C:12]([CH2:11][C:9]1[N:10]=[C:6]([NH:5][C:3](=[O:4])[CH2:2][NH:1][C:38]2[N:37]=[C:36]([N:34]3[CH:35]=[C:30]([CH:20]4[C:19]5[CH:58]=[CH:59][C:16]([CH2:14][CH3:15])=[CH:17][C:18]=5[CH:24]=[CH:23][C:22]5[CH:25]=[C:26]([CH3:29])[CH:27]=[CH:28][C:21]4=5)[C:31](=[O:57])[NH:32][C:33]3=[O:56])[CH:41]=[CH:40][N:39]=2)[S:7][CH:8]=1)#[N:13]

Participants

3

Reactant 2

HCID 18689744HCID 18689744, compoundHCID 54523132HCID 54523132, compound

Product 1

HCID 18689746HCID 18689746, compound

Procedure

The subtitle compound was prepared from the product of step (iii) (1.58 g) and the product of example 15 step (viii) (1.14 g) by the method of example 7 step (i). Yield 0.7 g.

Sources & evidence

ORD record
ord-9c0a9aae55884ae2a677c8a8c3a89c6d
Source dataset
uspto-grants-2000_08
Patent number
US06107297

Reaction notes

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