HCID 178420617, compound → HCID 178511438, compound

Participants

Reaction Steps

The product of step (i) (1.4 g) was slurried in ethyl acetate, washed with 1N HCl and filtered. The filtrate was washed with water, dried (MgSO4) and evaporated. The residue was dissolved in dichloromethane (50 ml) and trifluoroacetic acid (8 ml) and stirred at room temperature for 2 hours. The mixture was evaporated. The residue was azeotroped with toluene and triturated with isohexane. The product was collected by filtration. Yield 0.45 g.

Provenance & Evidence