1,4-Dioxane hydrochloride → HCID 69688232, compound

Participants

Reaction Conditions

Reaction Steps

(S)-[1-(4-Hydroxy-benzyl)-2-(4-hydroxy-piperidin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester (450 mg, 1.2 mmol) was dissolved in 4M HCl-dioxane (2 mL) at 0° C. The mixture was stirred at 25° C. for 1 hour, concentrated and the residue triturated with ether. Yield, 400 mg, 107%; MS 265 (MH+, 100%).

Provenance & Evidence