5,7-dichloro-1H-indole-2-carboxylic Acid → HCID 21710747, compound

HRID 1872191Notes

Reaction equation

HRID 1872191 reaction equation
ClC1C=C2C(=CC=1)N([N+:11]([O-:13])=[O:12])C(C(OCC)=O)=C2.[Cl:19][C:20]1[CH:21]=[C:22]2[C:26](=[C:27](Cl)[CH:28]=1)[NH:25][C:24]([C:30]([OH:32])=[O:31])=[CH:23]2>>[N+:11]([C:21]1[C:20]([Cl:19])=[CH:28][CH:27]=[C:26]2[C:22]=1[CH:23]=[C:24]([C:30]([OH:32])=[O:31])[NH:25]2)([O-:13])=[O:12]

Participants

3

Reactant 2

HCID 49832385,7-dichloro-1H-indole-2-carboxylic AcidHCID 54569596HCID 54569596, compound

Product 1

HCID 21710747HCID 21710747, compound

Procedure

The title compound was prepared by hydrolysis of ethyl 5-chloro-nitro-1H-indole-2-carboxylate as described for the preparation of 5,7-dichloro-1H-indole-2-carboxylic acid.

Sources & evidence

ORD record
ord-3a89c5e890804dc982d4aae48b887797
Source dataset
uspto-grants-2000_08
Patent number
US06107329

Reaction notes

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