5-Chloro-1H-indole-2-carboxylic acid → HCID 57025214, compound

HRID 1872202Notes

Reaction equation

HRID 1872202 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11]([OH:13])=O)=[CH:5]2.[CH3:14][O:15][C:16](=[O:31])[CH:17]([NH2:30])[CH2:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]2[NH:26][CH2:27][CH2:28][N:29]=2)=[CH:21][CH:20]=1>>[CH3:14][O:15][C:16](=[O:31])[CH:17]([NH:30][C:11]([C:6]1[NH:7][C:8]2[C:4]([CH:5]=1)=[CH:3][C:2]([Cl:1])=[CH:10][CH:9]=2)=[O:13])[CH2:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]2[NH:29][CH2:28][CH2:27][N:26]=2)=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 826935-Chloro-1H-indole-2-carboxylic acidHCID 53845088HCID 53845088, compound

Product 1

HCID 57025214HCID 57025214, compound

Procedure

From 5-chloro-1H-indole-2-carboxylic acid and (±)-2-amino-3-[4-(4,5-dihydro-1H-imidazol-2-yl)-phenyl]-propionic acid methyl ester.

Sources & evidence

ORD record
ord-6dade747fc8142e9bf7c916f4487b99b
Source dataset
uspto-grants-2000_08
Patent number
US06107329

Reaction notes

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