HRID1872315

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC=CC1=C(C(=O)OC(C)(C)C)N2C(=O)[C@@H](NC(=O)Cc3ccccc3)[C@H]2SC1

HCID54192859

未命名化合物

结构：CC=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)Cc3ccccc3)[C@H]2SC1

HCID54428718

未命名化合物

PRODUCTS

生成物

结构：CC=CC1=C(C(=O)OC(C)(C)C)N2C(=O)[C@@H](c3ccccc3)[C@H]2SC1NC(C)=O

HCID131721960

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

To a stirred solution of tert-butyl (6R,7R)-7-phenylacetamido-3-(1-propenyl)-ceph-3-em-4-carboxylate in dichloromethane (30 ml.g-1) was added Lewis acid (3-5 equiv., see table for conditions). The formation of (6R,7R)-7-phenylacetamido-3-(1-propenyl)-ceph-3-em-4-carboxylic acid was monitored either by HPLC or TLC. The results are summarized in the table.