1-Tetralone → 1,2-Dihydro-4-methylnaphthalene

HRID 1872479Notes

Reaction equation

HRID 1872479 reaction equation
[CH2:1]1[CH2:11][C:9](=O)[C:8]2[C:3](=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:2]1.[CH3:12][Mg]I>>[CH3:12][C:9]1[C:8]2[C:3](=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:2][CH2:1][CH:11]=1

Participants

3

Reactant 2

HCID 107241-TetraloneHCID 178418373HCID 178418373, compound

Product 1

HCID 5823271,2-Dihydro-4-methylnaphthaleneYield 68%

Procedure

α-Tetralone was reacted with methylmagnesium iodide as described in J. Org. Chem., 26, 4165 (1961), without isolation of the intermediate 1-methyl-1-tetralol, to give the desired product, after distillation, in 68% yield as a colorless oil, boiling point 55-57° C. at 0.8 mm Hg.

Sources & evidence

ORD record
ord-978dd5c8269b406ba9878751e6eaebc3
Source dataset
uspto-grants-2000_08
Patent number
US06110638

Reaction notes

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