HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1872583Generated: November 1, 2026
Hydrogen Bromide → 5-Bromo-5-(4'-phenoxyphenyl)barbituric acid
https://huagongshe.com/reaction/1872583
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 5-(4-Phenoxyphenyl)-1,3-diazinane-2,4,6-trione | HCID 11673778 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-Bromo-5-(4'-phenoxyphenyl)barbituric acid | HCID 22732233 | — |
Reaction Steps
To a suspension of 5-(4'-phenoxyphenyl)barbituric acid (48 mg)in 0.23 ml of water, cooled at 0° C. and under stirring, are added 23 μl of 48% hydrobromic acid and successively 9 μl of bromine. After 2 hours at room temperature additional 9 μl of bromine are added and stirring is continued for 2 hours. The suspended solid is then filtered and washed with water, to give, after drying under vacuum at 60° C., 57 mg of the product, m.p. 125-127° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06110924 |
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| Source dataset | uspto-grants-2000_08 |
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| ORD ID | ord-4605dd353cc443de858531ffca472627 |
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| Source note | uspto-grants-2000_08 |
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