Methyl iodide → HCID 12467927, compound

HRID 1872708Notes

Reaction equation

[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][N:8]=[CH:9]2)([O-:3])=[O:2].[CH3:14]I.[BH4-].[Na+]>>[CH3:14][N:8]1[CH2:7][CH2:6][C:5]2[C:10](=[CH:11][CH:12]=[CH:13][C:4]=2[N+:1]([O-:3])=[O:2])[CH2:9]1

Participants

Reactant 3

HCID 6328Methyl iodide

HCID 690855-Nitroisoquinoline

HCID 4311764Sodium borohydride

Product 1

HCID 12467927HCID 12467927, compound

Procedure

5-Nitroisoquinoline was quaternized with methyl iodide and then reduced using sodium borohydride according to the procedures of Preparations 1 and 2 to give the title compound.

Sources & evidence

ORD record: ord-33b112bed2404bb09f2fd646913383c2
Source dataset: uspto-grants-2000_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06110934

Reaction notes

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