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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1872712Generated: November 3, 2026

5-Chloro-o-anisic acid → N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-2-methoxybenzamide

https://huagongshe.com/reaction/1872712

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-o-anisic acidHCID 76970—
Reactant2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amineHCID 14171269—
ProductN-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-2-methoxybenzamideHCID 18687428—

Reaction Steps

The title compound was prepared in an analogous manner to Example 1 from 5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline and 5-chloro-2-methoxybenzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06110934
Source datasetuspto-grants-2000_08
ORD IDord-09976da0e0ad4a3ea8104760475f825c
Source noteuspto-grants-2000_08