4-Chloro-o-anisic acid → HCID 18687392, compound

HRID 1872713Notes

Reaction equation

HRID 1872713 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([CH3:12])[CH2:7]2.[Cl:13][C:14]1[CH:22]=[CH:21][C:17]([C:18](O)=[O:19])=[C:16]([O:23][CH3:24])[CH:15]=1>>[CH3:12][N:6]1[CH2:5][CH2:4][C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:18](=[O:19])[C:17]2[CH:21]=[CH:22][C:14]([Cl:13])=[CH:15][C:16]=2[O:23][CH3:24])[CH2:7]1

Participants

3

Reactant 2

HCID 936824-Chloro-o-anisic acidHCID 141712692-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine

Product 1

HCID 18687392HCID 18687392, compound

Procedure

The title compound was prepared in an analogous manner to Example 1 from 5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline and 4-chloro-2-methoxybenzoic acid.

Sources & evidence

ORD record
ord-6bb76d3c4e1641ae9c8934f05628943a
Source dataset
uspto-grants-2000_08
Patent number
US06110934

Reaction notes

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