2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine → N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-4-amino-5-iodo-2-methoxybenzamide

HRID 1872720Notes

Reaction equation

HRID 1872720 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([CH3:12])[CH2:7]2.[NH2:13][C:14]1[C:22]([I:23])=[CH:21][C:17]([C:18](O)=[O:19])=[C:16]([O:24][CH3:25])[CH:15]=1>>[CH3:12][N:6]1[CH2:5][CH2:4][C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:18](=[O:19])[C:17]2[CH:21]=[C:22]([I:23])[C:14]([NH2:13])=[CH:15][C:16]=2[O:24][CH3:25])[CH2:7]1

Participants

3

Reactant 2

HCID 141712692-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amineHCID 153457254-Amino-5-iodo-2-methoxybenzoic acid

Product 1

HCID 18687453N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-4-amino-5-iodo-2-methoxybenzamide

Procedure

The title compound was prepared in an analogous manner to Example 1 from 5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline and 4-amino-5-iodo-2-methoxybenzoic acid.

Sources & evidence

ORD record
ord-a4b353b3ea7c42f2aae1d31805df6d28
Source dataset
uspto-grants-2000_08
Patent number
US06110934

Reaction notes

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