2-Ethyl-1,2,3,4-tetrahydroisoquinolin-5-amine → HCID 18687446, compound

HRID 1872727Notes

Reaction equation

HRID 1872727 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([CH2:12][CH3:13])[CH2:7]2.[Cl:14][C:15]1[C:16]([O:26][CH3:27])=[CH:17][C:18]([O:24][CH3:25])=[C:19]([CH:23]=1)[C:20](Cl)=[O:21]>>[ClH:14].[CH2:12]([N:6]1[CH2:5][CH2:4][C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:20](=[O:21])[C:19]2[CH:23]=[C:15]([Cl:14])[C:16]([O:26][CH3:27])=[CH:17][C:18]=2[O:24][CH3:25])[CH2:7]1)[CH3:13]

Participants

3

Reactant 2

HCID 186873592-Ethyl-1,2,3,4-tetrahydroisoquinolin-5-amineHCID 186874425-Chloro-2,4-dimethoxybenzoyl chloride

Product 1

HCID 18687446HCID 18687446, compound

Procedure

The title compound was prepared in an analogous manner to Example 2 from 5-amino-2-ethyl-1,2,3,4-tetrahydroisoquinoline and 5-chloro-2,4-dimethoxybenzoyl chloride.

Sources & evidence

ORD record
ord-7288257257bf48b38be073eceee384cd
Source dataset
uspto-grants-2000_08
Patent number
US06110934

Reaction notes

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