2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine → N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-4-benzoyl-2-methoxybenzamide

HRID 1872732Notes

Reaction equation

HRID 1872732 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([CH3:12])[CH2:7]2.[C:13]([C:21]1[CH:29]=[CH:28][C:24]([C:25](O)=[O:26])=[C:23]([O:30][CH3:31])[CH:22]=1)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH3:12][N:6]1[CH2:5][CH2:4][C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:25](=[O:26])[C:24]2[CH:28]=[CH:29][C:21]([C:13](=[O:20])[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:22][C:23]=2[O:30][CH3:31])[CH2:7]1

Participants

3

Reactant 2

HCID 141712692-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amineHCID 186873604-Benzoyl-2-methoxybenzoic acid

Product 1

HCID 18687391N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-4-benzoyl-2-methoxybenzamide

Procedure

The title compound was prepared in an analogous manner to Example 1 from 5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline and 4-benzoyl-2-methoxybenzoic acid.

Sources & evidence

ORD record
ord-f51baaadb0b6402a806da267105d5c70
Source dataset
uspto-grants-2000_08
Patent number
US06110934

Reaction notes

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