2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine → HCID 131721962, compound

HRID 1872737Notes

Reaction equation

HRID 1872737 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([CH3:12])[CH2:7]2.[CH2:13]([C:15]1[C:23]([Cl:24])=[CH:22][C:18]([C:19](O)=[O:20])=[C:17]([O:25][CH3:26])[CH:16]=1)[CH3:14]>>[ClH:24].[CH3:12][N:6]1[CH2:5][CH2:4][C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:19](=[O:20])[C:18]2[CH:22]=[C:23]([Cl:24])[C:15]([CH2:13][CH3:14])=[CH:16][C:17]=2[O:25][CH3:26])[CH2:7]1

Participants

3

Reactant 2

HCID 141712692-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amineHCID 18687475HCID 18687475, compound

Product 1

HCID 131721962HCID 131721962, compound

Procedure

The title compound was prepared in an analogous manner to Example 1 from 5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline and 4-ethyl-2-methoxy-5-chlorobenzoic acid.

Sources & evidence

ORD record
ord-56699539a63d4999b9896202e6122144
Source dataset
uspto-grants-2000_08
Patent number
US06110934

Reaction notes

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