2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine → HCID 131721963, compound

HRID 1872738Notes

Reaction equation

HRID 1872738 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([CH3:12])[CH2:7]2.[C:13]([C:17]1[C:25]([Cl:26])=[CH:24][C:20]([C:21](O)=[O:22])=[C:19]([O:27][CH3:28])[CH:18]=1)([CH3:16])([CH3:15])[CH3:14]>>[ClH:26].[CH3:12][N:6]1[CH2:5][CH2:4][C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:21](=[O:22])[C:20]2[CH:24]=[C:25]([Cl:26])[C:17]([C:13]([CH3:14])([CH3:15])[CH3:16])=[CH:18][C:19]=2[O:27][CH3:28])[CH2:7]1

Participants

3

Reactant 2

HCID 141712692-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amineHCID 18687468HCID 18687468, compound

Product 1

HCID 131721963HCID 131721963, compound

Procedure

The title compound was prepared in an analogous manner to Example 1 from 5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline and 4-tert-butyl-2-methoxy-5-chlorobenzoic acid.

Sources & evidence

ORD record
ord-dd89045d1b094f6c87550bfc59d13641
Source dataset
uspto-grants-2000_08
Patent number
US06110934

Reaction notes

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