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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 187288Generated: October 30, 2026

Water → 1-Cyclohexyl-5-[4-(4-hydroxy-1-methyl-4-piperidinyl)-2-methoxyphenyl]-3-methyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

https://huagongshe.com/reaction/187288

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
Reactant1-Methyl-4-piperidoneHCID 74049—
ReactantHCID 136005882HCID 136005882—
ReactantButyllithiumHCID 178418339—
Product1-Cyclohexyl-5-[4-(4-hydroxy-1-methyl-4-piperidinyl)-2-methoxyphenyl]-3-methyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-oneHCID 136005933—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-1d40930b67884ec68d6b83ca6525bd71
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)