Ethanol → 5-Methyl-N-(piperidin-4-YL)pyridin-2-amine

HRID 187295Notes

Reaction equation

HRID 187295 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[n:16][cH:17][c:18]([CH3:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH3:22][CH2:23][OH:24].[OH-:25].[OH-:27].[Pd+2:26]>>[NH:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[n:16][cH:17][c:18]([CH3:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 230211122-(1-Benzylpiperidin-4-ylamino)-5-methylpyridine

Product 1

HCID 230210485-Methyl-N-(piperidin-4-YL)pyridin-2-amine

Sources & evidence

ORD record
ord-1663d377b0974bf5bb425e268c26f4cf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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