Acetonitrile → 4-(2,4-difluorobenzyloxy)-1-(3-fluorobenzyl)-3-iodo-1H-pyridin-2-one
Reaction equation
[CH3:40][C:41]#[N:42].[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][c:8](=[O:20])[n:9]([CH2:12][c:13]3[cH:14][c:15]([F:19])[cH:16][cH:17][cH:18]3)[cH:10][cH:11]2)[cH:21][cH:22][c:23]([F:25])[cH:24]1.[I:26][N:27]1[C:28](=[O:29])[CH2:30][CH2:31][C:32]1=[O:33].[OH:34][C:35]([CH:36]([Cl:37])[Cl:38])=[O:39]>>[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[c:7]([I:26])[c:8](=[O:20])[n:9]([CH2:12][c:13]3[cH:14][c:15]([F:19])[cH:16][cH:17][cH:18]3)[cH:10][cH:11]2)[cH:21][cH:22][c:23]([F:25])[cH:24]1Participants
5
Sources & evidence
- ORD record
- ord-9a2490c1d6d143beb104b504d877db25
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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