1,3-Bis(diphenylphosphino)propane → HCID 10857821, compound

HRID 1873091Notes

Reaction equation

HRID 1873091 reaction equation
[CH3:1]P(C)CCCP(C)C.C1(P(C2C=CC=CC=2)CCCP(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[CH2:39]=[C:40]([P:47](=[O:54])([O:51][CH2:52][CH3:53])[O:48][CH2:49][CH3:50])[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46]>>[CH2:39]=[C:40]([P:47](=[O:54])([O:51][CH2:52][CH3:53])[O:48][CH2:49][CH3:50])[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46].[CH:40]([P:47](=[O:54])([O:48][CH2:49][CH3:50])[O:51][CH2:52][CH3:53])=[CH:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:1]

Participants

5

Reactant 3

HCID 812191,3-Bis(diphenylphosphino)propaneHCID 43643001,3-BIS(DIMETHYLPHOSPHINO)PROPANEHCID 10857821HCID 10857821, compound

Product 2

HCID 10857821HCID 10857821, compoundHCID 54302676Diethyl oct-1-en-1-ylphosphonate

Procedure

Example 8 was repeated in the same manner as described except that 1,3-bis(dimethylphosphino)propane was substituted for 1,3-bis(diphenylphosphino)propane and that the reaction was carried out for 36 hours. The proton NMR analysis of the resulting reaction mixture revealed that an isomeric mixture of (a) dimethyl 1-octen-2-yl-phosphonate and (b) dimethyl 1-octen-1-yl-phosphonate was obtained with a yield of 85% and that the weight ratio of the former phosphonate (a) to the latter phosphonate (b) was 94:6.

Workup

  1. customThe proton NMR analysis of the resulting reaction mixture

Sources & evidence

ORD record
ord-a429f07d7a624d57a0cf53330b27dd2c
Source dataset
uspto-grants-2000_08
Patent number
US06111127

Reaction notes

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