Bromine → HCID 15481259, compound

Participants

Reaction Steps

Prepared from acetic acid 3-(6-bromo-benzo[b]naphtho[2,3-d]thiophen-11-yl)-phenyl ester (Example 38) according to the procedure for Example 41. White solid: mp 110-111° C.: NMR (CDCl3); δ 8.35 (dd, J=8, 1 Hz, 1H), 7.81 (d, J=8, Hz, 1H), 7.67-7.63 (m, 2H), 7.53 (dd, J=8, 7 Hz, 1H), 7.44 (ddd, J=8, 7, 1 Hz, 1H), 7.39 (ddd, J=8, 7, 1 Hz, 1H), 7.13-7.09 (m, 2H), 7.00 (dd, J=8, 1 Hz, 1H), 6.88 (dd, J=1, 1 Hz, 1H), 6.78 (dd, J=8, 1 Hz, 1H), 4.99 (s, 1H, OH); MS (EI): [M+], 1 bromine isotope pattern, 404 (95%), 406 (100%); Anal. Calc. for C22H13BrOS: C, 65.19, H, 3.23, N, 0.00. Found: C, 64.85, H, 3.51, N, 0.43.

Provenance & Evidence