Bromine → HCID 53968183, compound

Participants

Reaction Steps

Prepared from of 2,6-dibromo-4-(6-phenylsulfanyl-benzo[b]naphtho[2,3-d ]thiophen-11-yl)-phenol (Example 64) and (S)-2-hydroxy-3-phenylpropionic acid, methyl ester (Example 96). White solid: NMR (DMSO-d6); δ8.50 (d, J=8 Hz, 1 H), 7.98 (d, J=8 Hz, 1 H), 7.83 (d, J=2 Hz, 1 H), 7.81 (d, J=2 Hz, 1 H),7.71 (ddd, J=6, 5, 2 Hz, 2 H), 7.58 (m, 2 H), 7.47 (ddd, J=8, 8, 1 Hz, 1 H), 7.42 (d, J=8 Hz, 2 H), 7.34 (t, J=7 Hz, 2 H), 7.29-7.20 (m, 4 H), 7.17-7.08 (m, 3 H), 6.67 (d, J=8 Hz, 1 H), 5.35 (t, J=7 Hz, 1 H, CH), 3.41 (d, J=7 Hz, 2 H); MS (+FAB): [M+], 2 bromine isotope pattern, 738 (35%), 740 (90%) 742 (60%); Anal. Calc. for C37H24Br203S2: C, 60.01, H, 3.27, N, 0.00. Found: C, 58.57, H, 3.04, N, 0.22.

Provenance & Evidence